• Grant AD, Miller MM, Anastas TM, Quinn P, Lok B, Hirsh AT. Opioid-related risk perceptions in chronic pain: influence of patient gender and previous misuse behaviors. Pain. 2022 Apr 1; 163(4):711-718.
• Quinn PD, Chang Z, Bair MJ, Rickert ME, Gibbons RD, Kroenke K, D'Onofrio BM. Associations of opioid prescription dose and discontinuation with risk of substance-related morbidity in long-term opioid therapy. Pain. 2022 Apr 1; 163(4):e588-e595.
• Pickard JG, van den Berk-Clark C, Matthieu MM. Association of Medication-Assisted Treatment and Age With Treatment Completion Among Veterans Seeking Non-VA Treatment for Opioid use Disorder at Non-Veterans Health Administration Facilities. Military medicine. 2022 Mar 28; 187(3-4):504-512.
• Suda KJ, Evans CT, Gibson G, Jurasic MM, Poggensee L, Gonzalez B, Hubbard CC, Vivo A, Cunningham FE, McGregor JC, Gellad WF. Opioid Prescribing by Dentists in the Veterans Health Administration. American journal of preventive medicine. 2022 Mar 24.
• Guo J, Gellad WF, Yang Q, Weiss JC, Donohue JM, Cochran G, Gordon AJ, Malone DC, Kwoh CK, Kuza CC, Wilson DL, Lo-Ciganic WH. Changes in Predicted Opioid Overdose Risk Over Time in A State Medicaid Program: A Group-Based Trajectory Modeling Analysis. Addiction (Abingdon, England). 2022 Mar 21.

» View more Citations

• Predictive Tool Associated with 22% Lower Odds of All-Cause Mortality among High-Risk Veterans Taking Opioids
  In 2018, VA mandated a case review intervention that targeted patients who had been prescribed opioid analgesics and who were at high risk of adverse outcomes. The Stratification Tool for Opioid Risk Mitigation (STORM), a provider-facing dashboard that uses predictive analytics to stratify patients prescribed opioids based on their risk for overdose/suicide, was developed to identify these patient...
  
  Date: May 2, 2022
• High Virologic Cure Rates for Hepatitis C Virus among Veterans with Opioid Use Disorder Treated with Elbasvir/Grazoprevir
  Elbasvir (EBR)/grazoprevir (GZR) is a fixed-dose combination treatment for hepatitis C virus (HCV). This study sought to evaluate the real-world effectiveness of EBR/GZR among Veterans with HCV genotype (GT) 1 who also had a diagnosis of opioid use disorder (OUD). Findings showed that high rates of virologic cure were achieved among VA patients with HCV, OUD, and multiple comorbidities, including ...
  
  Date: January 25, 2022
• Death from Overdose Involving Stimulants Increasing in Veterans
  This study sought to describe trends in stimulant-alone and stimulant and other substance use overdose deaths among Veterans and to measure patient and treatment use characteristics across stimulant-related overdose death profiles. Findings showed that the rate of deaths among Veterans from stimulant-related overdose, alone and in combination with other substances, tripled from 2012 to 2018 with t...
  
  Date: October 14, 2021
• Veterans Do Not Always Receive Appropriate Continuation of OUD Medications During Surgical Hospitalizations
  This study sought to describe practice patterns of perioperative buprenorphine use within VA – and patient outcomes up to 12 months following surgery. Findings showed that the majority of VA surgical patients in this study who received buprenorphine for opioid use disorder experienced a dose hold at some point during the perioperative period despite a trend in clinical guidelines recommending bupr...
  
  Date: September 20, 2021
• Veterans Receiving Buprenorphine for Opioid Use Disorder Have Lower Risk of Suicide/Overdose Mortality
  This study sought to determine the association between buprenorphine pharmacotherapy and suicide, overdose, and all-cause mortality among Veterans initiating buprenorphine within VA. Findings showed that Veterans who were not receiving buprenorphine pharmacotherapy on any given day had more than a four-fold increase in suicide/overdose death compared to those who received buprenorphine, even when ...
  
  Date: May 19, 2021

» View more Publication Briefs

» View more Studies

• Evidence Brief: Transcranial Magnetic Stimulation (TMS) for Chronic Pain, PTSD, TBI, Opioid Addiction, and Sexual Trauma - Supplementary Materials

  ...(TMS) for Chronic Pain, PTSD, TBI, Opioid Addiction, and Sexual Trauma - Supplementary...(TMS) for Chronic Pain, PTSD, TBI, Opioid Addiction, and Sexual Trauma - Supplementary...(TMS) for Chronic Pain, PTSD, TBI, Opioid Addiction, and Sexual Trauma Supplementary

• Effects of VA Opioid Policy on Prescribing and Patient Outcomes || In Progress

  Effects of VA Opioid Policy on Prescribing and Patient Outcomes...Prescription Opioid Use among Veterans » Table of Contents Effects of VHA Opioid Policy...Patient-Centered Outcomes Ongoing Study Opioid analgesics are the most commonly prescribed

• State Prescription Monitoring Program to Evaluate Concurrent VA and Non-VA Opioid Prescriptions || In Progress

  In 2013, VA launched the Opioid Safety Initiative (OSI), the first of several...system-wide initiatives to address opioid overuse. As a result, by mid-2016 the...September 2018 In This Issue: Improving Opioid Safety » Table of Contents State Prescription...Evaluate Concurrent VA and Non-VA Opioid Prescriptions Feature Article Controlled

• Improving Opioid Safety || In Progress

  In 2013, VA launched the Opioid Safety Initiative (OSI), the first of several...system-wide initiatives to address opioid overuse. As a result, by mid-2016 the...This Issue: Improving Opioid Safety Overview: National Opioid Crisis Ongoing HSR&D...HSR&D Studies Effects of VHA Opioid Policy on Prescribing and Patient Outcomes

• Evidence Brief: Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain - Supplementary Materials

  Brief: Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in...Brief: Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in...Brief: Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in

» View more Publications

» View more Cyberseminars

Videos

There are currently no videos for this topic.

Podcasts

There are currently no podcasts for this topic.

Other Resources

• Learn more about VA HSR&D’s State of the Art conferences on opioid safety and non-pharmacological approaches to chronic musculoskeletal pain management.
• Learn more about the Quality Enhancement Research Initiative’s IMPROVE project, which focuses on integrating pain support in primary care in order to decrease the number of Veterans using opioid therapy for pain management.
• Visit the VA Office of Research & Development’s Substance Use Disorders (SUD) topic page for information about milestones in SUD research across all VA research services.