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Hepatitis C

Hepatitis C is a liver infection caused by the hepatitis C virus. Hepatitis C can range from a mild illness lasting a few weeks to a serious, lifelong illness. Hepatitis C is often described as “acute,” meaning a new infection or “chronic,” meaning lifelong infection. The virus is most commonly spread through sharing needles syringes, or other equipment used to inject drugs; accidental needle-sticks in healthcare settings; and being born to a mother who is already infected.  VA research into hepatitis C addresses prevention, treatment, and managing quality of life.

Each "widget" below is populated by a dynamic search of the HSR&D website and its underlying databases. Search results are generated based on the search term "Hepatitis C". Results are updated regularly, as new data are available.

VIEW: Citations | Publication Briefs | Studies | HSR&D Briefs, Reports, Newsletters | Topic Spotlight | Cyberseminars | Videos | Podcasts | Other Resources



Citations

(5 of more than 435 HEPATITIS C focused publications)



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Publication Briefs

(5 of more than 19 HEPATITIS C focused publication briefs)


  • High Virologic Cure Rates for Hepatitis C Virus among Veterans with Opioid Use Disorder Treated with Elbasvir/Grazoprevir
    Elbasvir (EBR)/grazoprevir (GZR) is a fixed-dose combination treatment for hepatitis C virus (HCV). This study sought to evaluate the real-world effectiveness of EBR/GZR among Veterans with HCV genotype (GT) 1 who also had a diagnosis of opioid use disorder (OUD). Findings showed that high rates of virologic cure were achieved among VA patients with HCV, OUD, and multiple comorbidities, including ...
    Date: January 25, 2022
  • Veterans Advocate Treating “Sickest First” When Discussing Limited Resources for Hepatitis C Treatment
    Investigators in this study used Democratic Deliberation (DD) methods as a proof of concept for informing policy decisions related to the allocation of scarce resources for treatment of chronic hepatitis C virus in VA. Findings showed that most Veterans endorsed a sickest-first policy over a first-come-first-served policy, emphasizing the ethical and medical appropriateness of treating the sickest...
    Date: May 1, 2020
  • VA Successfully Implements Interferon-free Treatment for Hepatitis C Virus in Previously Undertreated Patient Populations
    This study examined the adoption of interferon-free treatment for hepatitis C virus (HCV) in VA to learn who received this therapy and whether the limitations of interferon-containing treatments have been overcome, including low rates of use among VA healthcare users who are African American or Hispanic, and among those with HCV-HIV co-infection. Findings showed that with the advent of interferon-...
    Date: March 7, 2018
  • HCV-Related Complications Increasing among Women Veterans
    This study examined gender-related differences in the incidence and prevalence of cirrhosis, decompensated cirrhosis, and hepatocellular cancer (HCC) between 2000 and 2013. Findings showed that the incidence and prevalence of hepatitis C virus (HCV) complications was higher in men than in women. However, the rate of increase in the incidence rates of cirrhosis and decompensated cirrhosis among HCV...
    Date: November 1, 2017
  • Direct-Acting Antiviral Agents Reduce Risk of Hepatocellular Cancer among Veterans with Hepatitis C
    This study examined the risk of hepatocellular cancer (HCC) following sustained virological response (SVR) among 22,500 Veterans with hepatitis C virus (HCV) who received directing-acting antivirals (DAA) treatment at any of 129 VA hospitals between January and December 2015. Findings showed that in Veterans treated with DAAs, SVR was associated with a 76% reduction in the risk of developing hepat...
    Date: October 1, 2017

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Studies

( 5 of more than 27 HEPATITIS C focused projects )

Project No.  Title  PI  Funding Start   
IIR 16-024 Advanced Prediction Models to Optimize Treatment and Access for Veterans with Hepatitis C Waljee, Akbar 2017-04-01
IIR 14-322 Quality of Care for Hepatitis C in Veterans Who Are Homeless McInnes, Donald 2016-07-01
IIR 13-059 Care for Women Veterans with Hepatitis C Virus Infection Kanwal, Fasiha 2014-03-01
CRE 12-009 Web-based Intervention to Reduce Alcohol Use in Veterans with Hepatitis C Humphreys, Keith 2014-01-01
IIR 12-059 Cost-effective Uses of New Hepatitis C Treatments and their VA Budgetary Impact Owens, Douglas 2013-06-01

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HSR&D Briefs, Reports, Newsletters

5 sample "Hepatitis C" publications displayed.


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Topic Spotlight


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Cyberseminars

The most recent "Hepatitis C" seminars are displayed.
Date Title Presenter(s)
7/31/2019 Measuring Implementation Strategies to Inform Hepatitis C Quality Improvement: Lessons from the Field Yakovchenko, Vera  
Gonzalez, Rachel  
Park, Angela  
Rogal, Shari  
2/1/2018 Implementation Strategies and the Uptake of Hepatitis C Treatment in VA Rogal, Shari  
2/25/2016 Focus on Health Equity and Action: Treatment of HCV- ALD Among VHA Vulnerable Populations Julie, Lynch  
Uchendu, Uchenna  
DuVall, Scott  

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Videos


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Podcasts


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Other Resources

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