Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients.

Saunders J, Nambi V, Kimball KT, Virani SS, Morrisett JD, Lumsden AB, Ballantyne CM, Dong JF, ELIMIT Investigators. Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2011 Mar 1; 53(3):668-75.

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Abstract:

Between 5% and 27.5% of PAD patients were Persistent PRs to ASA over 6- to 12-month follow-up using different platelet assays. Further, these commonly used platelet assays show weak agreement in determining poor response to aspirin.