Validation of a type 2 diabetes screening tool in rural Honduras.

Milton EC, Herman WH, Aiello AE, Danielson KR, Mendoza-Avelarez MO, Piette JD. Validation of a type 2 diabetes screening tool in rural Honduras. Diabetes Care. 2010 Feb 1; 33(2):275-7.

Related HSR&D Project(s)

• RCS 03-155 – Research Career Scientist Award

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Abstract:

OBJECTIVE: To validate a low-cost tool for identifying diabetic patients in rural areas of Latin America. RESEARCH DESIGN AND METHODS: A regression equation incorporating postprandial time and a random plasma glucose was used to screen 800 adults in Honduras. Patients with a probability of diabetes of > or = 20% were asked to return for a fasting plasma glucose (FPG). A random fifth of those with a screener-based probability of diabetes < 20% were also asked to return for follow-up. The gold standard was an FPG > or = 126 mg/dl. RESULTS: The screener had very good test characteristics (area under the receiver operating characteristic curve = 0.89). Using the screening criterion of > or = 0.42, the equation had a sensitivity of 74.1% and specificity of 97.2%. CONCLUSIONS: This screener is a valid measure of diabetes risk in Honduras and could be used to identify diabetic patients in poor clinics in Latin America.