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Suda KJ, Traversa A, Patel U, Poggensee L, Fitzpatrick MA, Wilson GM, Evans CT. Uptake in newly approved antibiotics prescribed to patients with carbapenem-resistant Enterobacterales (CRE). Infection control and hospital epidemiology. 2021 Nov 24; 1-4.
We assessed trends in treatment of patients with CRE from 2012 through 2018. We detected decreased utilization of aminoglycosides and colistin and increased utilization in extended-spectrum cephalosporins and ceftazidime-avibactam. We found significant uptake of ceftazidime-avibactam, a newly approved antibiotic, to treat CRE infections.