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An evidence map of treatments for infantile epilepsy.

Apaydin EA, Partikian A, Rollison J, Baxi S, Fu N, Hempel S. An evidence map of treatments for infantile epilepsy. Epilepsy Research. 2021 Dec 1; 178:106781.

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Epilepsy prevalence is high among infants, but treatment guidelines are not clear. We conducted a scoping review of interventions to manage epilepsy in infants, and identified 37 studies. Most studies reported that interventions were effective (22 studies; 76 %), but randomized controlled trials were uncommon (7 studies; 19 %) and sample sizes were small (range: 2 to 284 participants; mean: 69.4; 95 % confidence interval: 49.5, 89.2). Additional high quality research and systematic reviews on interventions for infantile epilepsy are needed to establish better treatment guidelines for the disease.

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