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NAFLD and HCC: Time to Bridge the Gap.
Cholankeril G, Kanwal F. NAFLD and HCC: Time to Bridge the Gap. Hepatology (Baltimore, Md.). 2021 Nov 1; 74(5):2336-2338.
Nonalcoholic fatty liver disease (NAFLD) is the leading etiology for chronic liver disease, affecting over 25% of the global population.(1) The spectrum of NAFLD is diverse, ranging from steatosis to a more progressive form, nonalcoholic steatotohepatitis (NASH) that can lead to fibrosis and cirrhosis. NAFLD is emerging as one of the leading risk factors for hepatocellular cancer (HCC). Despite the growing concern for HCC attributed to NAFLD, the precise HCC risk according to the presence and severity of NAFLD is not well established.