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Livorsi DJ, Nair R, Lund BC, Alexander B, Beck BF, Goto M, Perencevich EN. MRSA prevalence and hospital-level antibiotic use: A retrospective study across 122 acute-care hospitals. Infection control and hospital epidemiology. 2021 Mar 1; 42(3):353-355.
We evaluated the relationship between local MRSA prevalence rates and antibiotic use across 122 VHA hospitals in 2016. Higher hospital-level MRSA prevalence was associated with significantly higher rates of antibiotic use, even after adjusting for case mix and stewardship strategies. Benchmarking anti-MRSA antibiotic use may need to adjust for MRSA prevalence.