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Health Services Research & Development

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Sarah L. Krein, PhD, RN – Research Career Scientist

Sarah L. Krein, PhD, RN Sarah L. Krein, PhD, RN
VA Ann Arbor Healthcare System
Ann Arbor, MI 


Sarah Krein, PhD, RN, is a Research Career Scientist at the VA Ann Arbor Center for Clinical Management Research (CCMR). She is also the Rensis Likert Collegiate Research Professor and a Research Professor of Internal Medicine at the University of Michigan, with an adjunct appointment in the School of Nursing. She is co-director of the CCMR research core, the VA Ann Arbor Healthcare System Clinical Research Mentorship Program, and a VA Patient Safety Center of Inquiry focused on preventing device-associated harm among hospitalized patients.

Dr. Krein has a clinical background as a nurse, multidisciplinary health services research training (with concentrations in health economics, research methods, and epidemiology), and expertise in the use of qualitative methods and implementation research. Her research includes the use of mixed methods and implementation science approaches with a focus on patient safety and management of complex chronic conditions. This includes studies that involve large-scale implementation of patient safety practices, mixed methods studies of disease transmission, provider communication and hospital resuscitation care, as well as trials of novel approaches for managing chronic pain.

Embracing the concept of team-based science and applying mixed methods and implementation research techniques to better understand and ultimately improve healthcare safety, quality, and effectiveness have been consistent themes of Dr. Krein's research over the past decade. Given her methodological expertise and diverse content knowledge, she has been continuously funded through grant support from VA, NIH, AHRQ, and CDC, both as a Principal Investigator and as a co-investigator on projects with collaborators across the University of Michigan as well as throughout the U.S. and internationally.

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