Blast-related Injuries
The prevalence of service members’ exposures to improvised explosive devices (IEDs) and other explosives in Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) led VA to undertake extensive systematic investigations into blast-related injuries. This research aims to generate high-quality evidence that can be directly translated into improved clinical practice, screening and diagnostic tools, and effective treatment strategies for Veterans with blast-related injuries.
HSR’s blast injury research includes developing diagnostic capabilities to distinguish among the different categories on the spectrum of blast injuries; assessing short-, mid-, and long-term outcomes among service members and Veterans after blast exposure; exploring the complex relationships and overlapping symptoms between blast exposure and other conditions such as traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and depression, and understanding the differences in outcomes between TBIs related to blast exposure and TBIs from other mechanisms.
Each section below is populated by a search of the HSR website. Search results are generated based on the search term "Blast" . Results are updated as new data are available.
VIEW: Citations | Publication Briefs | Studies | HSR Briefs, Reports, Newsletters | Cyberseminars | Videos | Podcasts | Other Resources
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Citations
(recent BLAST publications)
- Shi AA, Andrawis AS, Biswas A, Wilson FP, Obeid W, Philbrook HT, Go AS, Ikizler TA, Siew ED, Chinchilli VM, Hsu CY, Garg AX, Reeves WB, Prince DK, Bhatraju P, Coca SG, Liu KD, Kimmel PL, Kaufman JS, Wurfel MW, Himmelfarb J, Parikh CR, Mansour SG, ASSESS-AKI Consortium*. Using vascular biomarkers to assess heart failure event risk in hospitalized patients with and without AKI. BMC nephrology. 2025 Jun 2; 26(1):271, DOI: 10.1186/s12882-025-04169-1.
- Vandiver AR, Torres A, Sanden A, Nguyen TL, Gasilla J, Doan MT, Martirosian V, Hoang A, Wanagat J, Teitell MA. Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. Aging cell. 2025 Mar 1; 24(3):e14402, DOI: 10.1111/acel.14402.
- Jain K, Katz R, Isakova T, Kizer JR, Sharma S, Psaty BM, Shah SJ, Ix J, Mehta R. Association of Fibroblast Growth Factor 23 and Cardiac Mechanics in the Cardiovascular Health Study. Kidney360. 2025 Mar 1; 6(3):391-399, DOI: 10.34067/KID.0000000643.
- Mohammed HAO, Reavis KM, Thapa S, Thielman EJ, Helt WJ, Carlson KF, Hughes CK. Blast Exposure, Tinnitus, Hearing Loss, and Postdeployment Quality of Life in U.S. Veterans: A Longitudinal Analysis. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2024 Dec 1; 45(10):1204-1211, DOI: 10.1097/MAO.0000000000004332.
- McIntire A, Miller T, Thapa S, Joseph A, Carlson KF, Reavis KM, Hughes CK. Blast Exposure Associations With Hearing Loss and Self-Reported Hearing Difficulty. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2024 Nov 1; 171(5):1370-1378, DOI: 10.1002/ohn.890.
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Publication Briefs
(recent BLAST Publication Briefs )
- High TBI Screening Rates among OEF/OIF Veterans
This study describes the early results of VA’s TBI screening program, and identifies patient and facility characteristics associated with receiving a TBI screen. Findings showed that TBI screening rates are high in VA, with more than 90% of eligible Veterans screened. Of Veterans who were screened, 21% met the VA definition of a positive screen, with blast or explosion the most common exposure re...
Date: March 1, 2013
- Post-deployment Health Outcomes Associated with Multiple Deployment-Related Factors
This study examined the unique contributions of various deployment-related exposures and injuries to current post-deployment physical, psychological, and general health outcomes in National Guard members. Findings showed that various deployment-related experiences increased the risk for post-deployment adverse mental and physical health outcomes, individually and in combination. Most adverse outco...
Date: November 1, 2012
- Effect of Environmental Exposures on Non-Specific Physical Symptoms in OEF/OIF Veterans
Reporting of environmental exposures was relatively low in OEF/OIF Veterans, but reporting more environmental and other exposures, in particular screening positive for TBI, was related to greater non-specific physical symptom severity immediately after deployment. Soldiers reported higher rates of exposure to blasts than to any other single exposure: 15% reported exposure to one blast, 9% to two ...
Date: June 1, 2012
- Special Issue of Pain Medicine Highlights VA Research on Pain among OEF/OIF Veterans
This publication is in follow-up to a Pain Research Summit held in September 2007 by VA’s Rehabilitation R&D Service and VA/HSR&D’s Polytrauma and Blast-Related Injury Quality Enhancement Research Initiative (PT/BRI-QUERI). This Special Issue begins with four articles that build on the growing epidemiological literature on the prevalence and correlates of pain among OEF/OIF Veterans, and considers...
Date: October 1, 2009
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Studies
| Project No. |
Title |
PI |
Funding End |
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RCS 17-297
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Research Career Scientist Award |
Pugh, Mary Jo |
2028-06-30 |
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IIR 16-230
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Recommendations and Interventions for and Changes in the Ocular Health and visual Function of Veterans with Traumatic Brain Injury |
Scott, Steven |
2022-03-31 |
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IIR 13-294
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Impact of Sexual Assault and Combat-Related Trauma on Fertility in Veterans |
Mengeling, Michelle |
2021-01-31 |
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RRP 13-440
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Progressive Tinnitus Management: An Assessment of Readiness |
Henry, James |
2015-09-30 |
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SDR 08-267
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Telerehabilitation for OIF/OEF Returnees with Combat-Related Traumatic Brain Injury |
Siddharthan, Kris |
2014-06-30 |
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HSR Briefs, Reports, Newsletters
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Cyberseminars
The most recent "Blast" seminars are displayed.
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| Date |
Title |
Presenter(s) |
| 7/24/2024 |
Impact of Deployment Trauma on Photosensitivity and Visual Function
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Fortenbaugh, Francesca
Gustafson, Jennifer
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| 5/10/2023 |
Massed vs Intensive Outpatient Prolonged Exposure for Combat-Related Posttraumatic Stress Disorder
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Peterson, Alan
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| 1/11/2023 |
The DoD/USU Brain Tissue Repository: On the Front Lines of Investigating the "Invisible Wound" of Modern Warfare
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Perl, Daniel
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| 5/17/2022 |
Auditory Effects of Blast-Exposure in Service Members and Veterans
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Kubli, Lina
Melissa, Papesh
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| 4/26/2022 |
Recent Advances in Neuroimaging of Veterans with Mild traumatic Brain Injury, Sub-concussive Exposure, and Posttraumatic Stress Disorder
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Morey, Rajendra
Salat, David
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Videos
There are currently no videos for this topic. |
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Podcasts
There are currently no podcasts for this topic. |
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