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Griffin C, Agbim U, Ramani A, Shankar N, Kanwal F, Asrani SK. Underestimation of Cirrhosis-Related Mortality in the Medicare Eligible Population, 1999-2018. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2023 Jan 1; 21(1):223-225.e3.
The burden of cirrhosis may be increasing, especially among the elderly. A recent updated definition of cirrhosis has a > 90% positive predictive value for identifying cirrhosis and cirrhosis-related complications. We hypothesized that cirrhosis-related mortality is underestimated, and that the elderly are disproportionally impacted. In this study, we aimed to examine trends in liver-related mortality using this updated definition among the elderly and to identify changes by relevant subsets of gender, race, and rurality.